Welcome to the HIMS-Biocat website

HIMS-Biocat is a high multidisciplinary team of enthusiastic researchers working at the interphase between the biological and chemical sciences. Our aim is to develop new biocatalytic systems for the sustainable manufacture of chemical products (industrial biotechnology) as well as to address fundamental questions of biological chemistry. We believe that the advancement in the field of biocatalysis can meet the changing needs of industry in the next couple of decades and has a decisive impact on the future of the next generations on our planet. Part of our mission is also to train students such that they possess the necessary combination of skills in chemistry, biology and engineering needed to work in biocalysis. HIMS-Biocat, led by Dr. Francesco Mutti, is part of the Van’t Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam (UvA). HIMS-Biocat is located at the Amsterdam Science Park.

Biocatalysis: A sustainable solution to chemical problems

Biocatalysis is a high multidisciplinary science that encompasses bio-organic chemistry, biochemistry, molecular biology, protein engineering, bio-informatics and computational chemistry. Biocatalysis is founded on the use of the most powerful catalysts present in nature: the enzymes. Enzymes, also known as biological catalysts, are responsible of thousands of metabolic processes that sustain our life and the life of all the organisms on our planet. Since thousands of year ago, humans have started to exploit the “catalytic power” of enzymes, for instance, for the brewing of beer and wine or for the processing of food. During the past decades, enzymes (or cells containing enzymes) have been increasingly used to replace many traditional chemical catalysts, including catalysts that are not efficient or toxic or contain chemical residues that pollute the environment or require hazardous reaction conditions. Moreover, enzymes are capable of catalysing challenging chemical transformations with improved efficiency and exquisite selectivity. It is therefore possible to use natural enzymes as well as to create artificial enzymes in laboratory (i.e. enzyme engineering) to convert simple and inexpensive molecules into valuable chemicals for the manufacture of pharmaceuticals, cosmetics, plastics, textile fibres, etc.


Francesco Mutti

tel: +31 (0) 20525 8264

email: F.Mutti@uva.nl


Van´t Hoff Institute for Molecular Sciences

University of Amsterdam

PO Box 94157

1090 GD Amsterdam, The Netherlands

Visiting adress:

Science Park 904

1098 XH Amsterdam, The Netherlands

› directions to Science Park


We thank our partners:

HIMS Biocat - Amsterdam University
HIMS Biocat - Amsterdam University
HIMS Biocat - Amsterdam University